Reviewed by PeptideGuide Research Team|Last updated February 15, 2026
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GHK-Cu vs Matrixyl (Palmitoyl Pentapeptide-4)
Complete side-by-side comparison of GHK-Cu and Matrixyl (Palmitoyl Pentapeptide-4).
Side-by-Side Comparison
Property
GHK-Cu
Matrixyl (Palmitoyl Pentapeptide-4)
Name
GHK-Cu
Matrixyl (Palmitoyl Pentapeptide-4)
Peptide Class
Copper-binding peptide
Cosmetic Peptide
Category
Recovery and Repair
Skin and Cosmetic
Dosage Range
Varies based on formulation and application
N/A
Half-Life
N/A
N/A
FDA Status
Not FDA-approved for systemic use
Not FDA approved for medical use
Safety Rating
Generally Well-Tolerated
Generally Well-Tolerated
Cost Estimate
$100-200/month
$30-60 per month
GHK-Cu
GHK-Cu, or Glycyl-L-histidyl-L-lysine-Copper(II), is a copper-binding peptide renowned for its role in skin repair and anti-aging treatments. It enhan...
View full profile →Matrixyl (Palmitoyl Pentapeptide-4)
Matrixyl, also known as Palmitoyl Pentapeptide-4, is a cosmetic peptide primarily used in anti-aging skincare products. It is renowned for its ability...
View full profile →