Reviewed by PeptideGuide Research Team|Last updated February 15, 2026
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Melanotan II vs Melanotan I
Complete side-by-side comparison of Melanotan II and Melanotan I.
Side-by-Side Comparison
Property
Melanotan II
Melanotan I
Name
Melanotan II
Melanotan I
Peptide Class
Melanocortin receptor agonist
Melanocortin receptor agonist
Category
Melanocortin
Melanocortin
Dosage Range
0.5-2 mg per dose
0.16 mg/kg every other day
Half-Life
30-60 minutes
30 hours
FDA Status
Not Approved
Approved for specific conditions
Safety Rating
Use With Caution
Prescription Required
Cost Estimate
$150-300/month
$200-400/month
Melanotan II
Melanotan II is a synthetic peptide that mimics the effects of the melanocortin hormone, primarily used for its ability to induce skin tanning and enh...
View full profile →Melanotan I
Melanotan I, also known as Acetyl-[Nle4, D-Phe7]-α-MSH, is a synthetic peptide that functions as a melanocortin receptor agonist. It is primarily used...
View full profile →